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KMID : 1005420040060010011
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Journal of Cerebrovascular and Endovascular Neurosurgery
2004 Volume.6 No. 1 p.11 ~ p.15
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Hemodynamic Pathogenesis of AVM
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Lee Sei-Young
Kim Bum-Tae
Hwang Sun-Chul
Im Soo-Bin
Shin Won-Han
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Abstract
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Significantly decreased perfusion pressure is common in vascular territories irrigating neuronal tissue in patients with AVMs. There is evidence that ’adaptive autoregulatory displacement’ occurs in these patients which maintains cerebral blood flow above ischemic levels. Chronic arteriolar vasodilatation does not usually lead to vasomotor paralysis because most patients maintain a constant cerebral blood flow in spite of increased systemic arterial pressure. AVM hemodynamics appears to play an important role in the etiology of spontaneous intracerebral hemorrhage. Large AVM with high-flow and severe arterial hypotension are least likely to hemorrhage. In patients with AVMassociated aneurysm, the etiology of these dual lesions is likely multifactorial, with hemodynamic stresses having a dominant influence.
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KEYWORD
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Adaptive autoregulatory displacement, AVM hemodynamics
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